Efalizumab (Raptiva) review

raptivaEfalizumab, (AKA Raptiva), is an injected treatment obtainable solely by prescription. Primarily used for psoriasis, Efalizumab can also be utilized in some extreme, managed sorts of arthritis which don’t reply to the normal therapy.

How does Raptiva work?

Efalizumab works to deal with psoriasis by inhibiting T-cells within the immune system. For this reason it’s believed to be helpful in some kinds of arthritis which might be auto-immune in origin.

The safeness for use by pregnant ladies or lactating moms

Completely NOT! Girls who’re pregnant or planning to change into pregnant shouldn’t obtain Efalizumab due to the danger of fetal toxicity. It’s not identified if Efalizumab is present in breast milk. Do NOT breast-feed whereas taking Efalizumab.

Potential Raptiva side effects

Properly, let’s examine…the frequent “minor” unwanted effects embody pimples; again ache; headache; muscle aches; nausea; swelling within the arms or legs; vomiting. Some extra critical negative effects embody extreme allergic reactions (rash; hives; itching; issue respiration; tightness within the chest; swelling of the mouth, face, lips, or tongue); blood within the stool; darkish urine; dizziness when standing or sitting up; fainting; listening to modifications or listening to loss; an infection or flu-like signs (e.g., fever, chills, cough, sore throat, stiff neck); new growths or lumps; new or worsening arthritis signs (e.g., joint ache, redness, stiffness, swelling); new or worsening nervous system issues (e.g., confusion; lack of stability; numbness, tingling, or weak spot within the arms, legs, or face; bother strolling or speaking); purple, swollen, blistered, or peeling pores and skin; extreme or persistent headache; shortness of breath; uncommon bruising or bleeding; uncommon tiredness or weak point; imaginative and prescient modifications; worsening of psoriasis; yellowing of the pores and skin or eyes. OMG! Folks TAKE this drug?

Dangers of drug interactions

Immune system suppressing medicine (resembling cyclosporine) interacting with Efalizumab can improve the chance of extreme infections or most cancers!

Drawbacks & limitations

Efalizumab works to deal with psoriasis by inhibiting T-cells within the immune system. The chance of an infection all through the physique from a wide range of organisms, together with (however not restricted to) a virus liable for inflicting mind infections is extra doubtless in sufferers taking Efalizumab.

Efalizumab could improve the chance for critical and generally deadly infections! Different infections could embody bacterial sepsis, viral meningitis, invasive fungal illness, and different opportunistic infections.

You shouldn’t use Efalizumab when you have most cancers, low blood platelet ranges, or a extreme an infection or when you have PML. (Actually, I am unable to think about ANY cause you’d wish to use this drug…!)

References

http://www.nlm.nih.gov/medlineplus/ency/article/000434.htm

http://www.drugs.com/cdi/efalizumab.html