Alefacept (Amevive) review

ameviveAlefacept (AKA Amevive) is a prescription-solely injectable drug that manipulates one’s immune system in the remedy of psoriasis. It requires a weekly go to to the doctor for an injection instantly into the muscle tissue. Alefacept is used to deal with reasonable to extreme psoriasis and can also be used in psoriatic arthritis and for control of its symptoms.

How does Amevive work?

Psoriasis and the resulting psoriatic arthritis are caused by the triggering of immune cells often called T cells. Alefacept blocks this triggering mechanism in some T cells and eliminates others, which helps forestall the unfold of psoriasis.

The safeness for use by pregnant ladies or lactating moms

Nope, probably not. Pregnant or nursing ladies are often suggested to not take Alefacept and it’s unknown whether the drug is present in the milk of nursing mothers.

Potential Amevive side effects

The minor negative effects might embody cough, nausea, dizziness, muscle aches, sore throat, headache and itching. Nevertheless, some unfortunate people also can develop cancer, liver damage, infections and pneumonia!

Dangers of drug interactions

Alefacept can potentially work together with a couple of different medications. Some of the medication that will result in interactions with Alefacept embody: Echinacea “Reside”, vaccinations together with: Chickenpox vaccine (varicella vaccine), MMR vaccine (measles, mumps, and rubella vaccine), Polio vaccine, Rotavirus vaccine, Smallpox vaccine, Yellow fever vaccine, BCG vaccine (used in some nations for tuberculosis) and another immune-suppressing medications.

Drawbacks & limitations

This medicine must be injected as soon as each week for six months which is often a very lengthy, expensive and uncomfortable experience for a lot of patients. Alefacept is given in 12-week cycles by muscular injection of 15 milligrams per week. Then, patients are suggested to attend 12 weeks after the primary cycle in the event that they need a second cycle.

This is often a very painful and unbearably lengthy strategy of remedy for most people. Lastly, since Alefacept instantly affects T cells, docs often perform weekly blood tests to test levels. They might have to cease the medication if blood tests present a low amount of T cells.

References

http://www.webmd.com/pores and skin-problems-and-remedies/psoriasis-remedy-11/injectables

http://www.psoriasis.org/Document.Doc?id=216