What are main arthritis treatment methods
Not all medications that reduce pain, stop the progress of rheumatoid arthritis (RA). However, RA is a painful disease, because analgesic treatment plays an important role in RA process. RA causes inflammation of the symptoms of the disease, so that the anti-inflammatory resources, reduce inflammation and reduce pain in the joints so as long as long running each specific anti-inflammatory and analgesic.
Although that these products reduce the pain and swelling and a little sore performance of the body, but have no impact on the joints of bone structure damage, so it does not stop a disease – RA. Therefore, they are used as an additional means until such time as starts synthetic disease-modifying anti-rheumatic agents – that is an average of two to three months, or until the start operational biological disease-modifying anti-rheumatic agents, if any, necessary for a particular patient.
Non-steroidal anti-inflammatory drugs (NSAID) are divided into three groups:
- Non-selective COX I and COX II inhibitors – diclophenac, ibumetin, Ketoprofen, indomethacinum;
- Selective COX I and COX II inhibitors – were created to take care of more gastrointestinal tract, compared with non-selective COX I and COX II inhibitors – nimesulide, aciclopheum, meloxicam, Nimesulide, ceclofenac, nabumetone, Lornoxicam;
- Specific or selective COX II inhibitors – the adverse effects of drugs on the gastrointestinal tract – ro-fecoxib, celecoxib and increase anti-inflammatory and analgesic effect -celecoxib, etoricoxib.
Disease-modifying anti-rheumatic synthetic materials
The role of RA treatment is to stop the inflammation of the joints so that it would prevent deformation of the joint development and other organ involvement in RA process. Methotrexate, leflunomide, sulfasalazine, hydroxychloroquine – other reparations of this group are used in some cases the synthetic disease-modifying anti-rheumatic agents do not an immediate effect. Mostly treatment effect appears only after several weeks of use. It is important to understand and know the fight against RA.
Analgesics or pain medications
Reduces pain more than inflammation. Used if the pain does not inflammation or if you need to increase the anti-inflammatory analgesic effect. Para- cetamols, codeine, tramadol.
Non-steroidal anti-inflammatory drugs
They have several groups, depending on the efficiency and risk getting stomach – intestinal tract and cardio – vascular damage, as well as the potential to alter renal function. They are among not combing, but they can be combined with pain medications Use the lowest therapeutic dose needed to reduce or facing the pain.
Biological disease modifying anti-rheumatic agents (antibodies body processes involved in biologically active substances). Genetically produced medicines made from living microtions – viruses, genes or proteins, and then they are used in the human body treatment. Vaccines are the same method produced biological agents.
Biological drugs are targeted against inflammation, they can be use to treat- rheumatoid arthritis, juvenile idiopathic arthritis or psoriasis arthritis – inflammation and thus the disease process was stopped. The inflammation resulting from the immune system self attack, causing pain and destruction of the joints, as well as systemically effective – fatigue, heart and lung disease.
This medication is used for biological and malignant tumors. Usually biological medication is used when previous treatment with synthetic (chemically synthesized), disease-modifying anti-rheumatic agents have not been effective. Biological disease-modifying drugs are usually used in conjunction with synthetic disease-modifying anti-rheumatic products because the combination is more effective than one biological medicine treatment of rheumatoid arthritis.
TNF-alpha blockers – historically the first biological disease-modifying anti-rheumatic drug group:
- IL-1 blocker;
- IL-6 blockers – tocilizumab;
- CD20 blocker – rituximab.